Natural circular peptide inbhibitors of human prolyl oligopeptidase modulate caspase signalling in T-cells
The interdisciplinary team led by Roland Hellinger (Principial Investigator), Jonathan Dieringer & Paula Schwarz (equally contributing first authors) from the Department for Physiology and Pharmacology, Medical Universtiy of Vienna have published their study „Natural circular peptides regulate T-lymphocyte proliferation by inhibiting prolyl oligopeptidase“ in Biomedicine & Pharmacotherapy (BIOPHAR) (IF 7.5:2025).
Here is the link to the publication!
Jonathan Dieringer, Paula Schwarz, Kirtikumar B. Jadhav, Andreas Fraunhofer, Tobias Gökler, Anne C. Conibear, Christian W. Gruber, Roland Hellinger, Natural circular peptides regulate T-lymphocyte proliferation by inhibiting prolyl oligopeptidase, Biomedicine & Pharmacotherapy, 2026, 204, 120017; https://doi.org/10.1016/j.biopha.2026.120017.

